INTRODUCTION
Dear Friends and Colleagues,
It gives us a great pleasure to invite you to inflammatio 2018 that will take place in Tel Aviv, November 27-29, 2018. The first inflammatio meeting was in Chennai, India in 2016.
In addition to the International Symposium on Uveitis (ISU) this is a major conference on uveitis that will take place every 4 years, giving experts in uveitis an excellent chance to critically assess the current knowledge and the ‘state-of-the-art’ in intraocular inflammation. As such disorders often are connected to other systemic or organ disorders, a multidisciplinary approach will be followed in this meeting and experts from other fields of medicine and basic scientists will be invited as speakers.
The idea of inflammatio is to have a high standard forum for discussing challenging uveitis topics. The program will include important aspects in diagnostics, surgery and treatment.
We would like to invite you to participate actively in the meeting, since the core of the meeting is aimed to have lots of discussions. Your active participation is no doubt critical for the success of the meeting. We would like to see you submitting an abstract for e-poster: the best posters will be also presented orally. Please note that we also have the uveitis imaging photo contest, to bring about your artistic skills.
The meeting will be held in Tel Aviv, the venue is the beautiful Dan Hotel on the Mediterranean Sea where we also have special rates for rooms. Other options are also available through the website.
Tel Aviv is a lively city that never stops and offers many recreational, cultural and gastronomic experiences. It is also a great base for touring the country. The group will organize tours through the country before and after the meeting.
We hope to see you all in inflammatio 2018
The Organizing Committee
Michal Kramer, Mamta Agarwal, Manfred Zierhut
Program
Welcome reception in the Dan hotel
Registration
Opening
Experimental Uveitis Models in 2018
Chairs: Rachel Caspi, Gerhild Wildner, James Rosenbaum
09:05-09:25 Regulation of Th17 response by IL-17: implications for autoimmunity Rachel Caspi
09:25-09:45 Lessons from experimental rat models for chronic and relapsing autoimmune uveitis Gerhild Wildner
09:45-10:05 Of mice and men and women James Rosenbaum
10:05-10:20 Discussion
Coffee Break
The Role of Microbiome in Uveitis
Chairs: James Rosenbaum, Rachel Caspi
10:45-11:00 Welcome to the World of Microbiota Nida Sen
11:00-11:18 Microbiome and the Eye-the good and the bad Rachel Caspi
11:18-11:38 Microbiome and Tuberculosis Florian Hoelzl
11:38-11:56 Microbiome and HLA-B27 James Rosenbaum
11:56-12:16 Virome and the Eye Jolanda D.F de Groot-Mijnes
12:16-12:30 Discussion
Lunch
Multimodal Imaging (MMI) for Inflammatory Outer Retinopathies
Chairs: Michal Kramer, Padmamalini Mahendradas, Antoine Brezin
13:30-13:42 What have we learned from MMI about inflammatory outer retinopathies Michal Kramer
13:42-13:54 Insights to outer retinopathies from OCTA and Adaptive Optics Padmamalini Mahendradas
13:54-14:04 Clues for inflammation by MMI of rarest entities Orly Gal-Or
14:04-14:16 Clinical application of Artificial Intelligence and Machine Learning Noam Bresiz
14:16-14:26 The way to use Artificial Intelligence and machine learning in Uveitis Diagnosis Antoine Brezin
14:26-14:36 How MMI changes our management of inflammatory outer retinopathies Padmamalini Mahendradas
14:36-14:45 Discussion
Coffee Break
Controversies
Chairs: Soon Phaik Chee, Emmett Cunningham, Rubens Belfort, Shiri Shulman
1. Systemic vs intraocular steroid therapy for acute toxoplasmic retinochoroiditis
pro systemic: Emmett Cunningham; pro intraocular: Rubens Belfort
2. Biologics vs immunosuppressives as first line treatment for JIA-induced uveitis
pro Biologics: Athimalaipet V. Ramanan; pro Immunosuppressives: Debra Goldstein
3. Treatment of Behcet´s Disease: anti-TNF vs interferon alpha
pro: anti-TNF-alpha: Shiri Shulman; pro: interferon alpha: Manfred Zierhut
Progression Markers
Chairs: Joke de Boer, Nilüfer Yalcindag, Manabu Mochizuki
16:15-16:25 Progression markers of Vogt Koyanagi Haradas Disease Nobuyoshi Kitaichi
16:25-16:35 Biomarkers for increased risk of developing uveitis in JIA Joke de Boer
16:35-16:45 Laser flare photometry can predict a recurrence in Behçet-uveitis Nilüfer Yalcindag
16:45-17:00 Discussion
Meeting cocktail at the Dan hotel
Registration (new participants)
Tuberculosis - From Infection to Inflammation
Chairs: Soumyava Basu, Reema Bansal
09:00-09:12 Immunology of general TB infection Florian Hoelzl
09:12-09:24 Immunology of ocular TB infection Soumyava Basu
09:24-09:36 Update of the the COTS-studies Reema Bansal
09:36-09:48 Clinical spectrum of “inflammatory” TB Vasconcellos-Santos Daniel
09:48-10:00 Quantiferon testing in endemic vs. non-endemic areas Soon Phaik Chee
10:00-10:15 Discussion
Coffee Break
Preparing for Intraocular Surgery in Uveitis Patients
Chairs: Nicholas Jones, Mamta Agarwal, Sofia Androudi
10:45-11:00 General principles of medical preparation for intraocular surgery in uveitis Nicholas Jones
11:00-11:15 Intra- and perioperative care during cataract surgery Mamta Agarwal
11:15-11:30 Preparing for glaucoma drainage and vitrectomy in uveitis Sofia Androudi
11:30-12:30 Round Table Moderator: Nicholas Jones Cristina Muccioli, Nisha Acharya, Matthias Becker
Lunch
Uveitis Related Macular Edema
Chairs: Francine Behar-Cohen, Sue Lightman, Marina Mesquida
13:30-13:50 Differences between Uveitis macular edema and other etiologies Francine Behar Cohen
13:50-14:00 Role of Cytokines in uveitis related CME Marina Mesquida
14:00-14:15 Macular edema-what have the MUST trials taught us Sue Lightman
14:15-14:30 Options for treatment of uveitis related CME Marina Mesquida
14:30-14:40 Biologics and uveitic CME Oren Tomkins
14:40-15:00 Discussion
Coffee Break
Future Protocols for Uveitis Trials
Chairs: Philip Murray, Ron Neumann
15:30-15:35 Introduction Philip Murray
15:35-15:50 The Problem of outcome measurements in uveitis trials Nisha Acharya
15:50-06:03 Clinical trials in uveitis-The Industry Perspective Ron Neuman
16:03-16:16 Clinical trials in uveitis-The Reading Center Perspective Marion Munk
16:16-16:29 Why previous uveitis trials often failed James Rosenbaum
16:29-17:00 Round Table: What would be your ideal uveitis trial Moderator: Philip Murray
Faculty dinner
Registration (new participants)
Biologic Agents for Uveitis
Chairs: Manfred Zierhut, Debra Goldstein, Eric Suhler, Martin van Hagen
09:00-09:12 Definition of “Failure” under biologic drugs Debra Goldstein
09:12-09:24 Biologics inducing uveitis Manfred Zierhut
09:24-09:36 Side effects of biologics and biosimilars Martin van Hagen
09:36-09:48 Off label biologics as the next step Eric Suhler
09:48-10:15 Discussion
Coffee Break
Case Reports
Chairs: Careen Lowder, Massimo Accorinti, Zohar Habot-Wilner
Mystery Cases - Israeli Uveitis Group
1. Psoriasis-associated progressive necrotizing scleritis: Six-year Follow-up Nadav Levinger, Hadassah Medical Center, Jerusalem
2. Bilateral swollen discs and vision loss in posterior uveitis Karin Herscu, Bnei Zion Medical Center, Haifa
3. A case so simple Oren Yovel, Kaplan Medical Center, Rehovot
4. Drainage device-double trouble Shamaly shamaly, Bnei Zion Medical Center, Haifa
5. A case report of an unusual neurological association with APMPPE Raz Gebstein, Meir Medical Center, Kfar Saba
6. Choroidal effusion – more than meets the eye Zohar Habot-Wilner, Tel Aviv, Sorasky, Medical Center, Tel Aviv
Presentation of the best 5 Posters and Photo Contest
Chairs: Massimo Accorinti
6. MicroRNAs as Biomarkers for Ocular Involvement in Juvenile Idoipathic Arthritis Shani Pillar
9. Evaluation of potential host antigen-specific biomarkers in Quantiferon supernatants as candidates for the diagnosis of intra-ocular tuberculosis Derrick Smit
19. Vertical hyper-replective lesions. An OCT finding in vitreoretinal lymphoma Gábor Gy. Deák
22. Pediatric Vogt-Koyanagi-Harada Disease Gustavo Budmann
28. PP-001, a new novel small molecule for intraocular treatment of uveitis- first results of a prospective multicenter trial Stephan Thutau
Lunch
Uveitis in Immune Incompetent Patients
Chairs: Nida Sen, Jyotirmay Biswas, Alejandra de-la-Torre, Radgonde Amer
13:30-13:42 AIDS associated Uveitis in 2018 Jyotirmay Biswas
13:42-13:54 Role of CMV in immune incompetence Alejandra dela Torre
13:54-14:06 Post-Transplantation-Lymphoproliferative disorders Manfred Zierhut
14:06-14:18 Immune mediated ocular toxicity following the use of Immune Checkpoint Inhibitors for malignancy Nida Sen
14:18-14:30 Carcinoma-associated Uveitis Radgonde Amer
14:30-15:00 Discussion
Organizing Committee
Speakers
Discover Tel-Aviv
Tel Aviv is a vibrant city which prides itself on its 24/7 pace. It is known as the “City which never sleeps” for good reason. Located on the Mediterranean coast, it is both the country’s commercial and cultural capital. The city combines a frenetic pace with a laidback seaside air.
Offering an incredible array of nightlife, trend setting restaurants, a variety of markets and shops, a buzzing cultural scene, fascinating museums, quaint neighborhoods, along with varied sporting and recreational activities, Tel Aviv has it all.
Founded in 1909 among the sand dunes, the city has grown into a vibrant, modern city and a sought-after tourist destination.
Culture
Tel Aviv is the undisputed cultural center of the country. Its diverse cultural offerings – including theater, opera, dance, music and art are to be found throughout the city.
There are also numerous museums and galleries, both large and small, throughout the city.
Eating is the undisputed national pastime, and Tel Aviv offers plenty of options when it comes to trying out the local cuisine and partaking in the city’s vibrant cafe culture.
Strolling around Tel Aviv
Rothschild Boulevard A stroll along Rothschild Boulevard from Herzl Street all the way to the Habima National Theater and the Charles R. Bronfman Auditorium, home to the Israeli Philharmonic Orchestra offers a glimpse into the real Tel Aviv urban lifestyle: Trendy restaurants, eclectic architecture, and people just enjoying life.
The area around Rothschild Boulevard also known as The White City - a UNESCO Heritage site, is a collection of more than 4,000 buildings, constructed in the Bauhaus or International style of architecture. Built in the 1920s and 30s, many buildings have been restored and today stand alongside tall modern tower blocks.
Neve Zedek, established in 1887 by a group of Jewish families who wished to escape the confines of over-crowded Jaffa. It has maintained its quaint character, and its alleys are home to a large variety of trendy restaurants and bars, ice-cream shops, numerous cafes and interesting shops as well as a few small museums. Stroll along Shabazi Street, but feel free to explore the adjacent streets as well.
Neve Zedek - with permission Tel Aviv FOOD ©
Old Jaffa, brimming with history, is today home to many artists. It has several shops, galleries and restaurants. Its quaint alleys offer plenty of opportunity to snap some unique photos.
Sarona established in 1871 as a German Templar Colony, is today a vibrant recreational area. With a food market, trendy shops, unique bars and restaurants it is popular with the locals and tourists alike.
The Namal (Tel Aviv Port) located at the northern end of the city, built in the late 1930’s, was a working port until the 60’s. Today it is a vibrant recreational area with shops, restaurants, clubs and numerous attractions.
Tel Aviv’s beachfront runs the length of the city, from north to south; perfect for an early morning/evening run or walk. There are numerous beaches, each with its own character. Coffee shops, beachside bars and bistros dot the landscape, ensuring that everyone has a place to chill at the end of the day.
Beaches with permission Tel Aviv FOOD ©
HaTachana (The Old Railway Station) inaugurated in 1892, this railway line ran between Jaffa and Jerusalem. The train was not known for its speed, as passengers would jump off to pick wild flowers or simply walk alongside the train, without any fear of being left behind. Today it is home to several quaint shops, coffee shops and restaurants.
Cycling
There are numerous cycle paths throughout the city and along the beachfront.
Diversify Markets of Tel-Aviv
Tel Aviv has several markets, both indoor and outdoor, each with its own particular character.Start with this local tip – almost every vendor, no matter which market you shop in, will pack your purchases in a plastic bag. We always recommend to bring your own shopping bag along.
Carmel Market
The Carmel Market, one of the best markets in Tel Aviv.
with permission Tel Aviv FOOD ©
Shuk HaCarmel offers an amazing array of fresh fruit and vegetables as well as halva, olives and cheese. It also has a large selection of cheap clothing. It’s almost always crowded and noisy, so be prepared… Open from around 8am.
HaCarmel St, just off Allenby St.
Sarona Market
Sarona Market offers a more up-market atmosphere. The food court offers an array of delicious dining options, to suit almost any palate. Explore the numerous restaurants and shops in and around the area.
3 Aluf Kalman Magen St. from 9:00 am
Tel Aviv Port Market
https://shukhanamal.co.il/english/
Located in the Namal (port), in the northern part of the city, the Shuk Hanamal (Port Market) offers a wide array of culinary treats. A combination food and farmers market, it offers several options for light meals. Once here, enjoy a stroll along the boardwalk and enjoy the laid back Tel Aviv lifestyle.
12 Namal Tel Aviv St., Hangar 12 – daily from 9am, Fridays from 7am.
Jaffa Flea Market
Shuk Hapishpishim, the Jaffa Flea Market offers a variety of items, from vintage furniture and wannabe antiques to souvenirs, clothing, and lamps. The surrounding streets and alleys offer a selection of old and new.
Olei Zion St– shops open around 9:00 am
Nahalat Binyamin – Arts & Crafts Market
The Tel Aviv artist market.
Credit: http://goisrael.com/
The Arts & Crafts Market takes place on Tuesday and Friday and is a great place to look for inexpensive gifts, glassware and jewelry. Stalls usually open between 9-10am and are generally there till late afternoon.ahalat Binyamin Street, vendors open between 9:00-10:00 am
Antique Market
Offering an eclectic array of antique goods and collectors’ items, this weekly market is held on Friday mornings in Givon Square between Ha’Arba’a St. and Hashmonaim St. in close proximity both to the TLV Fashion Mall, and Sarona.Only open on Fridays.
No part of this website may be copied without the express permission of InStyle Events.
Restaurants in Tel Aviv
Those are some of the recommended restaurants and places to eat with an enjoyable atmosphere and great tastes.
Reservations recommended
Claro – 23 Ha'arbaa St. located in a beautiful stone structure at Sarona http://www.clarotlv.com/indexEn.html
Mashya - 5 Mendeli St. http://www.mashya.co.il/en/
Taizu - AsiaTerranean Kitchen – 23 Menahem Begin Rd. www.taizu.co.il/en/
Brasserie –French/ Israeli cuisine opposite Rabin Square – 70 Ibn Gvirol St. www.taizu.co.il/en/
Coffee Bar – 13 Yad Harutzim St. www.coffeebar.co.il/en/
Shila – 182 Ben Yehuda St. Trendy restaurant, amazing food, beautiful presentation. http://en.shila-rest.co.il/
Manta Ray – Popular restaurant overlooking the beach. Don’t miss their wonderful selection of meze. 703 Yehezkel Kaufman St. mantaray.co.il/index.php/manta-ray-en
Turkiz - Sea and Sun, 6 Herzl Rosenblum St. www.turkiz-rest.co.il/english/
Topolopompo – 14 Ha-Solelim St. http://www.topolopompo.co.il/
Café Europa - 9 Rothschild Boulevard. Simple fare in a trendy location.
M25 - In the heart of the Carmel Market, frequented by enthusiastic carnivores, is not for the fainthearted. Dishes come without frills as do the surroundings. Their arais (kebab toasted in a pita) is not to be missed. Open from 12:00 till late. Closed Friday 15:00 - Monday 12:00. No reservations. 30 Simtat HaCarmel.St.
Benedict – Breakfast served all day and 24/7 Thurs & Fri – perfectly suited to the crazy Tel Aviv lifestyle! http://www.benedict.co.il/en/ http://www.benedict.co.il/en/benedict-rothschild/
Masada – Bistro open 24/7, 83 HaYarkon St. Located just next to the Dan Hotel, great sea views http://bistromasada.rest.co.il/
Lala Land – 131 Herbert Samuel St. Casual beach bar & restaurant right on the sand, just north of the Dan Hotel http://www.lalalandtelaviv.co.il/en/
Rustico – 42 Basel St. or 15 Rothschild Boulevard https://www.rustico.co.il/en/
Italkiya bapishpishim – Italian restaurant at the Jaffa Flea market, 16 Olei Tzion St. Jaffa http://italkiya.co.il/italkiya-bapishpishim/
Pu’aa – 8 Rabbi Yochanan St. in the Jaffa Flea market area. All furniture, crockery and décor originated in the Flea market, so don’t expect anything to match! https://www.rol.co.il/sites/eng/puaa
Vicky Cristina – Tapas & Wine bar, the Tachana, Koifman St. http://www.vicky-cristina.co.il/
Italkia Ba´Tachana - Italian restaurant at the Tachana
http://www.italiantlv.co.il/italkia-batachana/
Greco - Popular, noisy Greek taverna. 25 Grinberg St. http://en.greco.co.il/
Grinberg - Neighbourhood bistro/deli – popular with the locals. 25 Grinberg St. http://en.grinbergbistro.co.il/
The Bakery – great for a coffee and delicious pasty, Tel Aviv style, 7 Kol Israel Haverim St., Neve Zedek
Sun-Thu 7:00 - 20:30; Fri 7:00-17:00
Lechamim Bakery - open non-stop from 6am Sunday – 14:30 Friday, light meals and coffee, with delicious pastries and cakes. 103 Hashmonaim St. opposite TLV Fashion Mall.
Abulafia Bakery – 7 Yefet St. (Clock Tower Square) , Jaffa https://www.facebook.com/abouelafia/
Museums in Tel Aviv
The Tel Aviv Museum of Art
The Tel Aviv Museum of Art. goisrael.com
Beit Hatfutsot: The Museum of the Jewish People
Beit Hatfutsot: The Museum of the Jewish People, is located on the Tel Aviv University campus. The museum portrays Jewish life throughout the Diaspora. Currently undergoing refurbishment, there are still several interesting displays to be seen.
Eretz Israel Museum
http://www.eretzmuseum.org.il/e/
The Eretz Yisrael Museum, the Museum of the Land of Israel, has several pavilions featuring archaeology, glass, numismatics along with unique changing exhibitions. It is also home to the best museum shop in Tel Aviv – a great place to splurge out on unique gifts.
Reuven Rubin Museum
http://www.rubinmuseum.org.il/en/home/a/main/
Originally the home of Reuven Rubin, one of Israel’s most influential artists, today this museum showcases his work alongside other artists.
Museum of the History of Tel Aviv-Yafo
The Museum of the History of Tel Aviv-Yafo is situated in the former Town Hall of Tel Aviv, an impressive building also located in Bialik Street, interesting multimedia displays chronicle the fascinating history of this city from its establishment just 100 years ago, up until today.
Steinhardt Museum of Natural History
12 Klausner Street
This recently opened museum on the Tel Aviv University campus, promises to be a treat for natural history buffs.
Further Afield
Art Galleries
Gordon Street, between Ben Yehuda and Dizengoff Streets is home to several galleries.
Gina Gallery, 255 Dizengoff St. Offers an international collection of naïve art
Gerstein Gallery, 101 Ben Yehuda St. provides an opportunity to smile while discovering the artist’s unique pieces. http://www.davidgerstein.com/ https://www.facebook.com/gerstein.gallery
Ilana Goor Museum, 4 Mazal Dagim Street, Old Jaffa, offers an eclectic collection of this local artist’s work.
https://www.ilanagoormuseum.org/en/
Rothschild Fine Art Gallery 48 Yehuda Halevy St.
Sommer Contemporary Gallery, 13 Rothschild Blvd. Promotes Israeli artists internationally.
Music
The Israel Philharmonic Orchestra at the Charles R. Bronfman Auditorium, Tel Aviv:
Bernstein: Symphony no.3, “Kaddish”
Leonard Bernstein at 100 Excerpts from the films “The Gift of Music” and The Love of Three Orchestras”
28.11.2018 Wednesday 20:00
29.11.2018 Thursday 20:00
30.11.2018 Friday 14:00
Tel Aviv Museum of Art - Concert Program
Saturday 24 November 2018 20.00
LA TEMPESTA DEI SOLISTI 2
Elgar Cello Concerto in e minor Op. 85
Rechtman Variations on Ochi Chornye (Dark Eyes) for Violin, Cello and Orchestra
Bruch Violin concerto No. 1 in g minor Op. 26
http://www.tamuseum.org.il/concert-item/98634
Tuesday 27 November 2018 20.00
CONCERT NO. 1
J.S. Bach Brandenburg Concerto No. 3 in G major BWV 1048
Saint-Saëns Cello Concerto No.1 in A minor Op. 33 (arr.) Soloist: Margarita Balanas
Mendelssohn String Octet in E flat major Op. 20|
http://www.tamuseum.org.il/concert-item/98557
Social program
Tour to Jerusalem:
Tour to Jerusalem - David's Citadel
with permission Tel Aviv FOOD ©
Sunday, November 25th.
Meeting Point&Time : 8AM leaves Dan Tel Aviv Hotel
Tour includes: an English speaking guide, transportation from the Dan Tel Aviv Hotel, light meal + beverage.
Price: $100 per person. Price based on participation of 15 people and may change according to the number of participants.
Entry fees may be required.
Monday 26/11 : 17.30-19.00 Welcome reception at the Dan hotel
Tuesday 27/11 : 17.00 -19.00 Meeting cocktail at the Dan hotel
Tel Aviv Walking Tour
Friday, November 30th
Meeting Point&Time : 9AM , Dan Tel-Aviv Hotel
Tour includes: an English speaking guide
Price : $55 per person. Price based on participation of 10 people and may change according to the number of participants.
Entry fees may be required.
Please confirm your participation: diana@instyle-events.co.il
Transportation Airport-Hotel in Tel Aviv
Train
Exit the Arrivals Hall through Gate 03. The entrance to the train station will be immediately to your left. Tickets can be purchased at the Information/Cashier's office or from the adjacent ticket machine. For information about the station: https://www.rail.co.il/en/stations/ben-gurion-airport
To plan your trip, please click here: https://www.rail.co.il/en
"From where?" enter: Ben Gurion Airport
"Where to?" enter: Tel Aviv-Savidor Center. For information on the station: https://www.rail.co.il/en/stations/tel-aviv-savidor-center?tabname=tabParking
Cost: NIS 13.50 per passenger
From there: By taxi to Dan Tel Aviv Hotel, 99 Ha-Yarkon Street or other hotel.
Public Taxi
Exit the Arrivals Hall through Gate 03. To your left you find an authorized taxi rank. The price to Tel-Aviv is NIS134 NIS during the day, and NIS154 at night (fixed rate). +NIS5 for 3rd passenger; + NIS4 per piece of luggage.
If you prefer, you can request a metered fare.
You may find a 12% cheaper taxi, when exiting the terminal at the second floor (Gate 23): NIS118 day-fare, NIS136 NIS night-fare; +NIS5 for 3rd passenger; + NIS4 per piece of luggage.
To pre-book a taxi to the airport contact:
Hadar Lod Taxi - 03-9711103
HaCohavim Taxi - 08-9106106
Day fare NIS 105; Night fare NIS 115.
The trip may take between 30 – 60 minutes, depending on traffic conditions
Private Taxi - can be arranged through the organizing company - InStyle Events: instyle@instyle-events.co.il, +972-3-6426616
Your driver will wait in the Arrivals Hall with a sign bearing your name and will take you directly to the hotel. This taxi can take up to 3 people.
Price: 270 NIS
Returning to the airport - same cost - to be arranged through InStyle Events
*Please do not use non- authorized taxis (they may approach you at the door of the arrivals hall on your way out, offering their services).
* Cost of train and public taxis may differ, according to regulations or providers
* Payment must be made in Israeli shekels (NIS).
* Please ensure that you have the necessary amount in Israeli Shekels before leaving the terminal.
Contact Us
- instyle@instyle-events.co.il